ProMIS Neurosciences to Present at 2021 Alzheimer’s Association International Conference Abstracts …

promis neurosciences to present at 2021 alzheimers association international conference abstracts selected for oral and poster presentations

Sumary of ProMIS Neurosciences to Present at 2021 Alzheimer’s Association International Conference Abstracts selected for oral and poster presentations:

  • ProMIS Chief Scientific Officer, Dr. Neil Cashman will give an oral presentation entitled: “Selective targeting of intracellular misfolded, pathogenic TDP-43 with rationally designed intrabodies.
  • Dr. Johanne Kaplan, ProMIS Chief Development Officer, will present the poster entitled: “Conformational epitopes exposed on misfolded toxic forms of amyloid-beta, tau and alpha-synuclein directly contribute to their seeding activity.
  • ” The poster discusses conformational epitopes on misfolded proteins that represent unique targets for therapeutic antibodies.
  • Both presentations will be available on the ProMIS website (www.
  • com) after the AAIC® closes on July 30.AAIC® is the largest, most influential international meeting focused on advancing dementia science.
  • About the ProMIS PipelineProMIS Neurosciences’ lead therapeutic candidate, PMN310, is a monoclonal antibody for Alzheimer’s disease created with a novel, proprietary method for discovering and developing antibodies that can uniquely and precisely target toxic forms of otherwise normal proteins.
  • The Company’s proprietary target discovery platform is based on the use of two complementary thermodynamic, computational discovery engines – ProMIS and Collective Coordinates – to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins.
  • Using this unique precision approach, the Company is developing novel antibody therapeutics for AD, ALS and PD.

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